Salar de Uyuni comprises over 10,000km² in the Potosi region. The salt is over 10 meters thick in the centre. In the dry season, the salt plains are a completely flat expanse of dry salt, but in the wet season, it is covered with a thin sheet of water that is still drivable.

The standard tour heads south toward the southwest corner of Bolivia, by many fluorescent-coloured lakes that are created from a collection of different minerals from runoff from the surrounding mountains.